Package: dynafluxr
Type: Package
Title: Retrieve Reaction Rate Dynamics from Metabolite Concentration
        Time Courses
Version: 1.0.1
Authors@R: person(given = "Serguei",
                    family = "Sokol",
                    role = c("aut", "cre"),
                    email = "sokol@insa-toulouse.fr")
Description: Reaction rate dynamics can be retrieved from metabolite
        concentration time courses. User has to provide corresponding
        stoichiometric matrix but not a regulation model
        (Michaelis-Menten or similar). Instead of solving an ordinary
        differential equation (ODE) system describing the evolution of
        concentrations, we use B-splines to catch the concentration and
        rate dynamics then solve a least square problem on their
        coefficients with non-negativity (and optionally monotonicity)
        constraints. Constraints can be also set on initial values of
        concentration. The package 'dynafluxr' can be used as a library
        but also as an application with command line interface
        dynafluxr::cli("-h") or graphical user interface
        dynafluxr::gui().
License: GPL-2
Encoding: UTF-8
Depends: bspline (>= 2.5.0), nlsic (>= 1.1.1)
Imports: optparse, qpdf, arrApply, slam, gmresls (>= 0.2), shiny,
        shinyjs, shinyFiles
RoxygenNote: 7.3.2
Suggests: RUnit, knitr
VignetteBuilder: knitr
NeedsCompilation: no
Packaged: 2026-07-06 09:24:31 UTC; root
Author: Serguei Sokol [aut, cre]
Maintainer: Serguei Sokol <sokol@insa-toulouse.fr>
Config/pak/sysreqs: cmake make libjpeg-dev libuv1-dev libssl-dev
        zlib1g-dev
Repository: https://sgsokol.r-universe.dev
Date/Publication: 2025-07-10 14:50:09 UTC
RemoteUrl: https://github.com/cran/dynafluxr
RemoteRef: HEAD
RemoteSha: 2f55e54a64957ecc82c4213a98788e1f01c935fc